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Tatsuhiko Ooie Selected Research

geranylgeranylacetone (teprenone)

9/2007Mitochondria are targets for geranylgeranylacetone-induced cardioprotection against ischemia-reperfusion in the rat heart.
7/2005Effects of insulin resistance on geranylgeranylacetone-induced expression of heat shock protein 72 and cardioprotection in high-fat diet rats.
6/2005Oral administration of geranylgeranylacetone blunts the endothelial dysfunction induced by ischemia and reperfusion in the rat heart.
7/2003Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart.

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Tatsuhiko Ooie Research Topics

Disease

9Reperfusion Injury
12/2011 - 10/2002
7Insulin Resistance
12/2011 - 09/2003
6Ischemia
09/2007 - 10/2002
5Hyperthermia
12/2011 - 08/2006
3Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
07/2005 - 09/2003
2Atrial Fibrillation
05/2019 - 11/2007
2Hypoxia (Hypoxemia)
07/2007 - 05/2006
2Type 2 Diabetes Mellitus (MODY)
04/2005 - 10/2004
2Ventricular Tachycardia
11/2003 - 11/2003
1Cardiac Tamponade
05/2019
1Hemorrhage
05/2019
1Infarction (Infarctions)
05/2009
1Fibrosis (Cirrhosis)
11/2007
1Ulcer
09/2007
1Essential Hypertension
07/2005
1Cardiac Arrhythmias (Arrythmia)
05/2005
1Hyperinsulinism (Hyperinsulinemia)
04/2005
1Tachycardia (Tachyarrhythmias)
07/2003

Drug/Important Bio-Agent (IBA)

8HSP72 Heat-Shock ProteinsIBA
12/2011 - 07/2003
7Insulin (Novolin)FDA Link
12/2011 - 10/2002
4geranylgeranylacetone (teprenone)IBA
09/2007 - 07/2003
3Angiotensin IIIBA
12/2011 - 06/2004
3Creatine Kinase (Creatine Phosphokinase)IBA
05/2009 - 11/2003
3Streptozocin (Streptozotocin)FDA Link
11/2003 - 10/2002
2Phosphatidylinositols (Phosphatidylinositol)IBA
12/2011 - 08/2006
2Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
12/2011 - 08/2006
2candesartanIBA
12/2011 - 06/2004
2mitochondrial K(ATP) channelIBA
05/2009 - 09/2007
2Glyburide (Glibenclamide)FDA LinkGeneric
08/2006 - 11/2003
2Angiotensin Receptor AntagonistsIBA
07/2005 - 06/2004
1idarucizumabIBA
05/2019
1DabigatranFDA Link
05/2019
1AnticoagulantsIBA
05/2019
1Prothrombin (Factor II)IBA
05/2019
1Pharmaceutical PreparationsIBA
09/2007
1PotassiumIBA
09/2007
1Adenosine Triphosphate (ATP)IBA
09/2007
1Testosterone (Sustanon)FDA Link
07/2007
1Pioglitazone (Actos)FDA Link
08/2006
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
08/2006
1Glucose (Dextrose)FDA LinkGeneric
07/2005
1Heat-Shock Proteins (Heat-Shock Protein)IBA
07/2005
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
07/2005
1PerindoprilFDA LinkGeneric
07/2005
1Brain Natriuretic Peptide (Natrecor)FDA Link
07/2005
1Valsartan (Vals)FDA Link
07/2005
1AdrenomedullinIBA
06/2005
1Acetylcholine (Acetylcholine Chloride)FDA Link
06/2005
1Connexin 43 (Connexin43)IBA
05/2005
1C-Reactive ProteinIBA
04/2005
1Estrogens (Estrogen)FDA Link
11/2004
1AlbuminsIBA
10/2004
1Protein Isoforms (Isoforms)IBA
11/2003
1chelerythrineIBA
11/2003
1Protein Kinase C-epsilonIBA
11/2003
1Protein Kinase CIBA
11/2003
1Natriuretic PeptidesIBA
09/2003
1Atrial Natriuretic Factor (ANF)IBA
09/2003

Therapy/Procedure

2Catheter Ablation
05/2019 - 07/2003
2Induced Hyperthermia (Thermotherapy)
05/2006 - 11/2004
2Oral Administration
06/2005 - 07/2003
1Ischemic Postconditioning
05/2009
1Therapeutics
07/2005